Use of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with Promethazine with Codeine Oral Answer demands cautious thought of the effects to the father or mother drug, codeine, along with the active metabolite, morphine.Promethazine with Codeine Oral Alternative is made up of promethazine, a phenothiazine. Phenothiazines are associa